Claudia von Boeselager: Yeah. Perfect. Let's talk a little bit more about your book, The Science and Technology of Growing Young. First of all, congratulations on writing a book. Not everyone gets that far, so really fantastic. And I also love the title. I think it sums it up really nicely. What was the purpose behind writing the book?
What was your vision when you sat down to start writing it? 

Sergey Young: Yeah, so, well, a number of things, one in longevity, vision fund, we're looking at 200 companies a year and we allow to lapse to the minds, the thoughts of entrepreneurs and greatest scientists. And I thought, I just need to share it with the public.
It's such a unique access that we joined through our fund. And again, there are very few funds investing in longevity technologies today. So it's a very rare knowledge and I wanted to share it with the audience. So that's number one. Number two, longevity became such a confusing information space. I think it's always been like, but recently it's been a problem.
Like today you read, you need to do your stem cells injection, like immediately, and then tomorrow you read, well, it's FDA, hasn't approved it. So you just need to wait. It's very risky. And then this happens with everything like putting butter and your coffee. Coffee is right or wrong. Blueberries are great.
And then next week blueberries eroding it.

Claudia von Boeselager: It toxic.

Sergey Young: Yeah. It's toxic. And the acid from the blueberries erodes your stomach from inside. So a lot of people just going into the default mode, like if this is important enough, this will find me through the medical system. Otherwise, I'm not gonna bother because it's really confusing.
So I thought I just need to bring a more balanced view because we have a lot of brilliant scientists in our scientific advisory board, or the companies that we investing in, we have like access to the best technologies and I'm doing a lot of experiments. I'm not a biohacker actually am pretty conservative guy, but whenever I have access to something really modern, you know, I'm just doing that... 

Claudia von Boeselager: jumping on it.

Sergey Young: And, 

Claudia von Boeselager: You're one level down from the biohacker we have to coin a term Sergey 

Sergey Young: yeah... That's true, by the way. And I kind of thought, well, this is what I need to share with the public, and I also do believe that we are so focused today on like a negative side of the healthcare system today. So we actually forgot, and we don't really take time to celebrate, think about gene editing and gene therapy.
30 years ago, it took 13 years and 3 billion dollars in U.S. to sequence human genome. In fact, they actually wanted to stop the experiment after first two years because they managed to sequence like 1% of the human genome, so they quickly calculated that it's gonna be what a hundred plus to do that, and funny enough and likely the computing power has been more and more affordable and the cost of it has been democratizing itself and they finally completed, well, these days you can sequence human genome, like the most important parts in the course of few hours, and it's supposed $200.
Or 30 years ago, the gene editing in the form of, almost like the only technology which was available this days, which is CRISPR, like, genetic scissors. It's been available only to the people who had like nothing to lose on this planet. They were terminally ill, they were about to die and they become like the Guinea pig.
The only people. Yeah. The Guinea pigs.

Claudia von Boeselager: Yeah, exactly. Like a last resort experiment. 

Sergey Young: Well, right now we are participating in a gene therapy experiment on a global scale. I do believe it's a positive experiments, but like Moderna AstraZeneca. Well, this of all the outcome of gene therapy. Yeah, so that's amazing.
And this is what happened in the last 30 years, and it's gonna be more and more like our variables. I'm like four full of variables. I'm experiment. Beautiful!

Claudia von Boeselager: I've got the checks. 

Sergey Young: Yep. Yeah. Oura Ring here or continuous glucose monitoring 

Claudia von Boeselager: ... Okay. Yeah. I've got those as well.

Sergey Young: So like, If we had taken care of our cars with computers, with sensors, our body and our mind, you know, are much more important.
We should do that. So then watch the wearable space. All these apple watch feed beats, whoops will become our personalized healthcare devices. I think with addition of like measuring glucose in the blood and measuring our blood pressure in the next couple of years... 

Claudia von Boeselager: mm-hmm

Sergey Young: I think Samsung watch already launched this feature and it's gonna be 90 to 95% of the indicators that we would like to measure on a regular basis.

Claudia von Boeselager: I'd love to take a step back. And perhaps you can tell listeners where this journey to finding the protocol actually began. Have you always been fascinated with neurodegenerative diseases? How did you stumble if you will, on this path? 

Dr. Dale Bredesen: Yes. I was a freshman at the California Institute of technology. And I read a book about the brain called the machinery of the brain by Dean Wooldridge of T-R-W fame.
And he talked about the relationship between computers. and the brain and I was interested in computers and I thought, oh, this is really interesting. You've got this amazing computer inside your skull.

Claudia von Boeselager: Mm-hmm 

Dr. Dale Bredesen: With a huge number of synapses. And I started reading and got very, very interested in what the brain was all about and how it worked.
Ultimately, I got interested in why we have diseases of the brain and why there's such horrible diseases. You know, if you look at the various types of disease, the area of greatest biomedical therapeutic failure has been in the area of neurodegeneration

Claudia von Boeselager: mm-hmm 

Dr. Dale Bredesen: So, you know, again, as someone said, everyone knows a cancer survivor, no one knows an Alzheimer's survivor and a co-used.
You could say the same thing for ALS and Frontotemporal dementia. So...

Claudia von Boeselager: What is a book that you have gifted most often, some of your favorite books to gift.

Sakiko Reuterskiold: So one is the count of Montecristo yeah, it's just a page Turner and a great read. So I've gifted that quite a few times. And then in terms of science and sugar, the , oh, God, Doctor Lustig book.

Claudia von Boeselager: I think I've heard of him. Yeah. There's The Bitter Truth. 

Sakiko Reuterskiold: The Bitter Truth, sorry. Yeah.

Claudia von Boeselager: Dr. Lustig and, The Bitter Truth.

Sakiko Reuterskiold: Like he writes really well and he's very, passionate about particular fructose and so on, but he writes in a way that I think is accessible to most people and it just definitely alarms you to the issues with sugar.
And then also on a more sort of philosophical, spiritual side of thing is Perennial Philosophy by Aldous Huxley. So Aldou Huxley, you know, is famous for A Brave New World, mostly as a dystopian, like future kind of and so on, but he was an incredible writer, reader, intellectual, philosopher and he was the editor for the Encyclopedia Britanica for quite a while because he's read everything and he summarizes and synthesizes all this wisdom and learnings from different religions and spiritual practices and things from around the world and does it so eloquently and beautifully and humbly. I think his book, the Perennial Philosophy is just wonderful and so insightful.
And you basically don't have to read all the different spiritual traditions around the world because he's got them in there in such a succinct and deep way. And.

Dr. Joseph Raffaele: As far as books are concerned, you know, for understanding aging. I think even though it was written like more than 20 years ago, Steven Austad, he's a zoologist that does a lot aging. He wrote Why We Age was just getting into the field and talks about, need to use other models, mice to understand aging, cuz mice are optimized for short lifespans, not long lifespans.
And they're good for looking at certain diseases and you know, they're laboratory animals, but they're not really that great for studying aging, but he also talks about evolution and the evolutionary theory of aging, which I think is very important to understand if you're really gonna kinda go into aging.
I mean, you can go into as a biohacker and just say, look, I want performance, but some people go into with the idea that well, so that mess with mother nature. And that's the problem is that when you understand that mother nature didn't intend. We're not selected or evolved to live to 50, 80, 90. We mostly died in our thirties of unnatural causes.
And so there's no plan. It's, it's like you use the analogy of, of the car, or I use the analogy of the dentist, you know, the car is designed to work, you know, and have a warranty for five years after that, if you wanna be running it 15 years, you you've gotta keep on checking it, replacing parts, doing your diagnostics on it.
We do that in dentistry. You know, we, we just don't do it in medicine, but we're still just screening for disease instead of screening for health and health erosion starts a lot longer before disease. So you, that is really important to watch Michael Fossils's book on Revolution is very good and of course Sinclaire's book lifespan. Those are sort of the top ones. If you really wanna dive into cell biology then Michael's book Cells Disease and Human Aging is one of the bibles that I read. That's a lot of reading there, but you're always getting pointed to new stuff. 

Helen Reavey: Different books that I've been reading and really enjoyed atomic habits. So I think like habits that you form will definitely help set you up for the day, but also like your evening.
So, you know, that book is incredible. It really made me understand habits, addictions, different things like that. So, you know, addicted to chocolate or something like that, you know, tell yourself. Okay, I'm gonna eat this chocolate right now. Let's say it out loud. What different things that make you happy during day?
So if it is that piece of chocolate that makes you happy. 

Marie Cudennec: So there's a great book by Christiana Figueres, who's really sort of singlehandedly was the woman behind the Paris agreement in 2015, which seemed like the most impossible task at the time and she's amazing called The Future We Choose so I highly recommend that as a great read.
Another one as a more of an unusual one is, Sacred Cow which is an absolutely brilliant documentary and book do the documentary. If you can't, you know, you don't feel like doing, but the book does go into a lot more detail and it's very much promoting regenerative agriculture as pretty much the solution to climate change and dispelling a lot of myths around cows being the reason, you know, there's a lot of, and I won't go into it now, but she basically puts forward the nutritional environmental and ethical case for better meat and for regenerative agriculture. Yeah. That was a really, really fascinating read recently. I would say those are really probably my two most seminal ones that I kind of will go back to a lot.

Claudia von Boeselager: For listeners interested in understanding more about biohacking and optimizing health better what are some resources or books you recommend to start with? 

Dr. Mohammed Enayat: Okay. So I really like a book called Juvenescence: Investing in the Age of Longevity. If you read that.

Claudia von Boeselager: mm-hmm 

Dr. Mohammed Enayat: by and Jim Mellon. I like that book because for those people that are interested in what's the convergence of biohacking and longevity science.
It's written a few years ago, but it summarizes it very well, like "Where does biotechnology fit?", "Where does gene therapy fit?" It's written from the perspective of a biotechnology perspective rather than a biohacking perspective, but it gives you that lens of perspective, which is quite interesting.
Another book I really like is by Aki Hintsa who's resting peace. He passed away now he wrote a book called The Core.

Claudia von Boeselager: mm-hmm the call? C-A-L-L? 
 C-O-R-E. 

Dr. Mohammed Enayat: And he actually started a center called The Hintsa Performance Center, which they do a coaching around basic principles of health, as well as mindset.
And you can see the evolution of that, where you apply a bit of kind of basic health coaching. With how to control your state, but he's worked with formula one drivers and cool people. So that's a, that's a really cool book and inspired me a bit as well.

Claudia von Boeselager: And I'd love to take a deep dive into your book now, Thrive State -your blueprint for optimal health, longevity, and peak performance. So how did it go from having your own Eureka moment? Doing your own discovery, you had the Ted Talk. And what was your motivation behind putting it all in the book and, you know, bringing it all together and the bio model really getting it out there?
Can you talk a bit about that? 

Dr. Kien Vuu: Yeah. So I saw a lot of changes in my body as I went through my disease-reversing process. Mm-hmm , but I wanted to make sense of all of it. And I also wanted to put it together in a way that it's easy to understand. And also as a framework I can use to say, okay, can I diagnose, or can I help somebody else with this problem?
Because, you know, MAR medicine says: Hey, you get this medical history, but you're not asking questions, how much they're sleeping, what they're eating, you know, and all these other things in their life. So I wanted a tool I could use. And as I started to study health and epigenetics and antiaging and regenerative medicine, I started to know this, these patterns, right.

Claudia von Boeselager: Mm-hmm 

Dr. Kien Vuu: Well, what are the things to decrease depression, you know, like, okay, exercise, sleep better, eat better. 

Claudia von Boeselager: Like... 

Dr. Kien Vuu: ...your blood pressure. Okay. Exercise, sleep better. So all these different things are all these different diseases. What are all the common things are, are common they start to show up over and over and over again.
And once I started to understand that I started to understand. Okay. Disease isn't some isolated thing in one particular organ system, but it's because the cells aren't given what they need. And basically when the cells aren't given what they need, our body is not talking to each other in an optimal way.
That's when you get, you know, disease symptoms. And when I piece that all together, it was like, wow, this is really a good framework to approach life and health and made a lot of sense. And that's why I wanted to put it together one so that I had something. I could work with my clients with, and I found that once I evaluated somebody's bioenergetic state and where they were and as we started to address some of those things, a lot of their symptoms sort of disappeared.
That was really the crux of as the, putting it all into a system. And I go into the science of how the old way of thinking about health is, you know, you get stuff from mom and dad, which is your DNA, and that's the health that you're given. But that's actually not the case. Our DNA is not a fixed thing, you know?
If our DNA was fixed, you know, nothing was changeable. We would basically be a one cell thing because you know, you've got the same DNA in every single cell, but what makes your eye cell different from your lung cell different from your heart cell? Is that not all the genes are turned on in exactly the right time.
And it's how these genes are turned on and turned off on a moment to moment like microsecond to microsecond basis. That what determines how a cell behaves, that's how you get the different cells in your, your body. And that's how you get optimal health in your body as well is how this DNA is being expressed.
And it turns out that the DNA is constantly listening and interacting with the environment that's surround this bioenergetic state. And as I, you know, start to explain it this way, people were like, oh wow. I had no idea I can be in control of my bioenergetic state. So I find putting it in a framework that people can, can truly understand empowers them.
And when people can say, oh my God, I'm in the thrive state. That's something that people can reach for and really empowers them to do their own work.
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