Dr. Richard Johnson: And if you're on a low carb diet, you probably don't have to worry about. Because you don't, you're not eating the carbs that are required to, to convert the glucose to fructose. You should know that when you're in a low carb diet, your body is making glucose, you would call it glucose neogenesis. So glucose is in your blood, but it's being made from muscle and fat and you're not producing a lot of it, but when you're eating carbs, you can.

Dr. Richard Johnson: A large amount of glucose. 

Claudia von Boeselager: Is a, is a problem that's really helpful to understand as well. And I think, yeah, the key is with that water consumption, obviously barring those three scenarios just to hydrate the body and to give it the right risk, obviously then cutting down on salt.

Claudia von Boeselager: And again, I think just that education around reading labels and oh yeah. Salt is actually in pretty much. Anything. And even in, I was looking once at a packet of chocolate chip cookies and not only the amount of sugar in there, but the amount of salt that they were putting in there to neutralize the sweetness.

Claudia von Boeselager: It was...

Dr. Richard Johnson: Really wow. Wow. That's really interesting. I have a friend who's in the food industry and he's been. He started telling me about how all these foods get injected with salt and what they do is they inject meats and stuff and it makes the meat look bigger. Like a shrimp looks really bigger because it's been pumped with salt water.

Dr. Richard Johnson: And then the truth is that the it's actually much smaller. And when you put it on the. Frying panel all the water comes out, the salt stays and now you gotta process. Look at, sometimes it'll tell you whether or not it's been injected with things and salt water. Is a favorite thing to inject into these shrimp and stuff?

Dr. Richard Johnson: Oh my God.

Claudia von Boeselager: Actually really interesting what you were saying because literally a few weeks ago I was at my parents when I was making some shrimp, but I tried to always wear possible, find the wild caught shrimp. Now it was still an cell, but they don't shrink in size. And I was thinking how astoundingly would a difference.

Claudia von Boeselager: And I'm very worried that a lot of the shrimp, even if it says you have to really read the label, but a lot of them are farmed, filled with antibiotics, et cetera. Yep. That must be the telltale sign. how much the shrimp, when you warm it up shrinks or not? 

Dr. Richard Johnson: Yes, it shrivels up in front of you.

Dr. Richard Johnson: That process food. There's so many studies that show that if you can try to reduce your intake and process food, you can really help. And it's cuz of the sugar and salt, high fructose corn syrup and all these things, MSG.

Claudia von Boeselager: It's horrendous. Exactly. So I think I'm with seafood, it's finding that wild caught seafood and then for meats, right?

Claudia von Boeselager: The grass fed meat as well, and you can taste the difference. And I think it's moving away from having to have a huge steak every night to actually seeing it as like a, an exception, like a nice pleasure, a few times a week instead, and then other invest and buy the quality versus the quantity as well.

Dr. Richard Johnson: Yeah, grass fed is really better than grain fed. And I didn't really talk about this in my book, but it's really true with grass feeding. You get much more omega three and with the grain fed, you get more omega six in the meat, and there's really increasing evidence. And I do talk about this in the book about how omega3s are so healthy.

Dr. Richard Johnson: And omega six tends to be pro-inflammatory and these seed oils that are omega six, rich, not so good. And they interact with this fructose pathway. So if you give omega three, you can block some of the effects of sugar, especially on the brain. So if you give sugar, fruit dose to an animal. You can actually show that it can impair their ability to get through a maze.

Dr. Richard Johnson: And you can reverse that with omega3 wallet. Oil is a flax seed and fish that are rich and omega3 salmon. That's good.

Claudia von Boeselager: Rick, what would you say? And I'm just trying to hypothesize here, cause I know you are also amongs other the research scientist in you, but I'm looking at like a Venn diagram intersection of between salt ,sodium chloride, specifically fructose and all metabolic or many metabolic diseases. Would you almost say that combination is a major driver? 

Dr. Richard Johnson: Oh, it's unbelievable. And so one of the strong associations initially was yes. Sugar intake, salt intake. They're associated with obesity, they're associated with diabetes, the metabolic syndrome, fatty liver.

Dr. Richard Johnson: This is where the, my research was kidney disease and these kind of classic diseases then leading to heart disease and so forth. But what, one of the two incredible areas that we've started looking at is how the switch and the can also be important in cancer. And also how it's important in neurologic disease, especially dementia.

Dr. Richard Johnson: The cancer one is really interesting.

Dean Graziosi: Fear, self doubt, worry about putting yourself out there, afraid to fail when things shift, especially after two years of COVID and now inflation and looming recession, whatever insecurities or self-doubt or imposter syndrome you had is gonna be magnified. And you're like, Ooh, that's great. Thanks for that uplifting message, right?

Dean Graziosi: Yes. But if you know that wouldn't it be better to anticipate and prepare and fortify your mind, rather than reacting and that's what I'd love to challenge you to think about today is how do. you Feed your mind to fortify it against the enemy that's coming. And the enemy is that inner self doubt where you turn into the thermometer of life with your emotions going up and down by the news or your friends or the kitchen table talk rather than being the thermostat and saying: Hey! In times like these real success can be found on a whole nother level.

Dean Graziosi: Google, when the most money is made, it's usually during a recession, but it's by the few who look for opportunity, not obstacles and what's wrong. Robbins always says what's wrong is always available.

Claudia von Boeselager: Yes. 

Dean Graziosi: But so is what's right? 

Claudia von Boeselager: Yes. 

Dean Graziosi: So what I would say going into a shifting world is the first thing we have to do is go upstream and fortify the mind , whatever that takes.

Dean Graziosi: If it's listening to audios reading books, being with your family, praying to God, I don't know what it is, but find something to fortify your mind and train yourself to look for opportunity through this. That's the first thing I think more important than any.

Dr. Jay Wiles: You're helping to build resilience to your stress response. The body does not know the difference between you running like a marathon and you sitting there being stressed in a meeting. It experiences that exactly the same, all of the same, maybe not the severity of the response. It could be. There's some people who will get into a, a conference meeting, a board meeting and their heart rate will go up to 140, 150 and it looks like, yeah, They're like in a really good steady run, but the body doesn't know the difference.

Dr. Jay Wiles: What the body does know is how you react to it, how you respond to it. And so this is why we say, like, when we think about heart rate variability, when we think about stress resiliency, we want to think less about my intention is to increase my value. Know my intention is to really number one. Access or look to see what is my self-awareness of where my mindset is right now.

Dr. Jay Wiles: And then how can I then make a actionable approach to change my physiology in the moment that also helps to change my mindset around it. So for me, it's all about how do I use this stress, not how does this stress use me? How does it knock me down and throw me every which way, because in the past it really has. And for a lot of people, it can really shake, rattle and roll them because stress can just have a chokehold on them. So we think that there's, those two things, self-awareness, and then self-regulation like, what do we actually do about it in the moment? So finding your baseline is incredibly important.

Dr. Jay Wiles: So at Hanu the first thing that we do is that we look to see what is your upper ceiling. So where is like your high average, where's your low average, and then what's your actual baseline average so we basically create this box, like this window and we say, and then we gets better with times the more data that we get, the more that we can hone in the window, we can broaden it, or we can shrink it down.

Dr. Jay Wiles: We know that when people are in a stressful situation, physiologically or psychologically that heart rate variability is gonna significantly decrease. And so when it decreases below that threshold, and this is how we do it with Hanu is that you'll receive an alert, we'll say, "Hey, something looks like it's going on. We just wanted to check in..." And you had the ability to log like this is what was going on. I was engaging in more, my number one, like large scale stress response is email apnea. That is unconscious breath holding when I'm writing an email, especially if one's a little bit contentious and it happens to a lot of people but if I'm holding my breath while writing an email I'll look on my hand, I've got it right now.

Dr. Jay Wiles: And as I'm talking and stuff, heart rate goes up, HR goes down, I'll just see it, pull on it. And I'm like, oh, there it is. And that's when I can then engage in. I'm self aware. I'm engaging in like self-awareness now let's do some self-regulation and get myself back to my baseline range. And really what we say is with HRV normal is good.

Dr. Jay Wiles: Normal is best. We're not trying to say, Hey, let me inflate my HRV as high as I can. There is benefit to that. But really when you're experiencing a stress response, it isn't saying let me go down. I've got my HRV let's say my HRV baseline's 50, and it went down to 15. Oh, now let me get it up to 75 80.

Dr. Jay Wiles: That might be really difficult in that moment for you to do. I just want you to engage in some quick breath work techniques, some biofeedback techniques to just get you back up to your range, to your box is your happy place. So that's how we do it at Hanu and really nobody's doing it like that, which is why I've explained it.

Dr. Jay Wiles: That's why we built Hanu is because we wanted someone to have a reference that acted like a stress radar or monitor all day long, but also a stress coach. We give you something actionable to do in the moment that's accessible to you and is all about training, a different response to increase your fortitude and adaptability to stress.

Dr. Jay Wiles: That was probably a really long winded answer for your question. I hope I covered the basis there.

Claudia von Boeselager: I think it's super helpful as well because obviously speaking with different people around, biohacking and biofeedback and devices, they're like, what am I supposed to do with all this data that you guys really solve for that, and actually, proactively help people. So one is the awareness, as you were saying as well, but then, and I'd love to uncover a little bit like the tools and strategies and how you do it at hand. Over time you have the window, you have the ceiling, you have the floor, you have your sort of baseline and you see what's going on as well.

Claudia von Boeselager: What are some of the trainings that you offer? And I would assume that some of the trainings are done at a time not during the board meeting, but in terms of you, you get trained to do it so that when you're at the board meeting, you can then use those tools. So can you walk a little bit like that client journey and how the training works and then what are some of the tools and mechanisms that you recommend?

Dr. Jay Wiles: Yeah, absolutely. A lot of it has to do with intention. So the first thing that we want to know is what do you want resiliency for? What do you want stress resiliency for? So a good blanket, 30,000 foot view type response would be I want, better longevity, better health span.

Dr. Jay Wiles: Great. Great. Okay. So we'll focus on that aspect, but a lot of people it's I want increased cognitive performance, or I've worked with a lot of business professionals and executives who say, I want less emotional reactivity. Like I fire off the email and then I send it and think, "Oh goodness, can I retract? I regret it." Like that happens so often. Or they think, "Oh man, I shot some words outta my mouth that I'm not very proud of." Or "I, through some gestures with my hands at the car next to me when they cut me off in traffic" or "I, rolled down my window and yelled at 'em" like a lot of people like will say like in the moment everything takes over their stress response takes over anger, aggression, and then they just engage in the behavior and then they get the home.

Dr. Jay Wiles: They think my goodness, what was I doing? Or if it's like me, it's man, I said that word out loud. And my two boys are like sitting behind me. Great example, psychologists, Dr. Jay Wiles. It's like all those things. So how can we then have an intention of what do we wanna do? Increase, performance increase resiliency, just like engage in better relationships.

Dr. Jay Wiles: So it starts there. So once we know what you want to get out of this, then we can tailor, we can curate a personalized pathway or journey for you. And I wanna speak, I know I'm speaking directly to Hanu, but this doesn't have to be done with Hanu. The great thing about this is that any type of wearable that you have is gonna give you insight into your response.

Dr. Jay Wiles: A lot of the wearables are created for recovery, which this is a wonderful recovery tool. I always say that anytime you're not working out, you're recovering. So this can be a beautiful tool for that. But a lot of 'em again, they give you one static score that's taken, maybe typically overnight.

Dr. Jay Wiles: Whereas we do it differently when we're actually monitoring you all day long, continuously looking at fluctuations or changes in heart rate variability. So let's say for instance, a lot of people who are like using our platform now as like alpha testers. So they're first people on it who are like our close advisors.

Dr. Jay Wiles: They, a lot of these individuals just want like better overall fortitude and resiliency and want to enhance performance and whatever that, that they do. So the thing that we say is okay, the best response is that number one, we need to see what are those things that are of like ticking away at your resiliency?

Dr. Jay Wiles: So we have to create better. Self-awareness like, what are those things that are really like knocking down your nervous system? And it's having a hard time recovering from that. So that's key point number one, number two, is that when that experience happens and we alert you to it and you become self aware of how stress is impacting you at that time.

Dr. Jay Wiles: Then we always wanna follow up. And this is like operat conditioning, 101 in psychology. We always wanna follow up with the therapeutic or the response to that. And the reason is because we do want to indeed condition a different response. We want to condition a response that is different than what might be your normal response.

Dr. Jay Wiles: Maybe your normal response is that you fly off the cuff and you send that nasty email, or you hold your breath during an email and this everybody's gonna be like, oh, I know what Jay's, the, my problem is right. We then change that response by putting something else in there.

Dr. Jay Wiles: What does that typically look like? We like to use the single greatest, low hanging fruit, which is breathing. So this kind of comes back and I'll give a little bit of the psychophysiology and science behind this. This comes back to well, what is the single greatest influencer on the human's best response in the moment that can be done anywhere doesn't require technology.

Jim Law: The EPA environmental protection agency here in the U.S. did a study in 2021 to determine what percentage of time Americans spend indoors versus outdoors.

Jim Law: And it turned out that we spend 93% of our time indoors. 

Jim Law: I started tracking this shortly after we started in this business was the rate of chronic disease and the growth in increase in chronic disease in the us. And in five years ago, 45% of American adults had at least one form of chronic disease.

Jim Law: Last year six in 10 American adults have at least one form of chronic disease, 40% have two or more. And you say, okay what's the relationship here? I, think it really became more evident with the work of Dr. Jerry Tennant, who world renowned MD has quite an interesting story himself. There's a lot of information available about him and of his work, but he wrote a book called "Healing is Voltage". What he was able to prove is that all chronic disease has one common characteristic and that's inadequate cellular voltage. When we step back and say, okay we were designed to be in nature. We all feel better when we're in nature, but it's actually vital to our health and wellness. And if you think prior to modern day we, went outdoors all day long and worked outside, and then we came in and didn't have light.

Jim Law: So you slept you didn't have to worry about our circadian rhythms and things, but modern day life has introduced a lot of challenges to us. And one of them is the fact that we spend so much time being blocked from four key energies that exist in nature. That we'll, talk about a little bit more.

Jim Law: But at the same time being 'bombarded' by manmade energies. So things like cell phones and wifi and microwave, which are all around us and we don't have to debate if they're bad for your health, but I think we could all agree. They're not the kind of energies that nature intended for us to thrive on.

Jim Law: So in, in a nutshell, the lack of energy at the cellular level, is what we believe to be the root cause of much of this chronic disease. You simply don't have enough energy for your cells to function correctly and I'll let Jim touch on that in a minute. And what the BioChargers actually doing is replicating and amplifying those four energy types.

Jim Law: So that we can bathe your body with those energies in a very short period of time, 12 to 15 minutes, and give your body at the cellular level, the energy it needs to have proper cellular function. 

Jim Law: Jim can you talk a little bit more about the detail? 

Jim Girard: Sure, so as we started to look at what is this energy outside?

Jim Girard: And as I started to delve into it, further realized it was really these lightning discharges that we have on this planet. So most people don't realize it, but we have a hundred lightning strikes on the planet, every single second. Each one generates hundreds of thousands of harmonics and frequencies that span the entire spectrum of AM, FM, short waved, long wave, UHF, BHF microwave millimeter all the way up to visible light. 

Jim Girard: Now other planets are doing the same thing. They have their own local atmospheres that are generating their own storms. That also contribute to that. We also have the Sun doing the same thing, which is what we call solar flares and solar storms.

Jim Girard: And right now we're in another major solar flare solar storm, where 92 million miles away from the sun, it's generating so much of energy that it's actually disrupting communication here on earth. And when you look at that in totality to the rest of the universe, it's just a minor compared to what the rest of the universe is doing.

Jim Girard: So any spinning object is generating. Wide ranges of frequencies and harmonics that we call cosmic rays. Now here also on earth. We have the magnetic field generating from the earth as it's rotating, it's got the iron core, that's generating these magnetic fields that are also a very important part of life.

Jim Girard: And then there's that visible light component not just the natural sunlight, but the, light from the gases in the atmosphere that get excited to fluorescent that produces thousands of different wavelengths in that visible infrared, far-Infrared, near infrared, visible light ultraviolet spectrum.

Jim Girard: That's also vital for our life. And when we're in buildings especially large buildings that have concrete and rebar, they're literally blocking all that natural energy. And because we're spending so much of that time, it has a direct effect on that. Voltage it's within the cellular level.

Jim Girard: What we decided to do is actually replicate and amplify those energy levels much like nature does it through plasma discharge. So simply put the bio charges replicating these four different energy types to mimic what's happening in nature. We do a little bit different than what manmade does.

Jim Girard: So manmade is more of a continuous wave where pulsing, it just like nature does. 

Claudia: So incredible that you're able to consolidate the galaxy and the universe of energy right into one of, one of these devices as well.

Dr. Limor Goren: I'm much more attracted to the concept of food as medicine and like all the big philosopher is always new and every drug can be a poison or it can be a drug can be an official. It all has to do with the dose. So I started playing around with that and I started testing different olive oils and trying to see if olive oils themselves are could be toxic to cancer cells and not to normal cells.

Dr. Limor Goren: And I found that they could be. And actually that was a really interesting story. How the discovery came along. 

Claudia von Boeselager: Yeah, please share.

Dr. Limor Goren: Ah, so when we published the first study about oleocanthal were contacted by olive oil producers from Greece. That the olive oil they're making was tested and it was found to have the highest concentration of olecanthal, ever found in olive oil back then.

Claudia von Boeselager: Wow.

Dr. Limor Goren: In 2014 so that was exciting. And they offered to send us the olive oil. So they send us a bottle of the olive, a very fancy it's called the Governor. And, since I started actually selling the olive, cuz I believe in it so much. And I tasted it and it was nice and spicy and peppery.

Dr. Limor Goren: And that is something I knew at that time, that is a sign of oleocanthal. So when you try different olives in a supermarket or in a specialty store, if ethanol gives you a sting in the back of your throat, that's the sign of oleocanthal. So I knew it has a lot of oleocanthal and they sent me the, the proof that he does, but I was wondering if I can treat cancer cells with olive oil. So I poured some of that Governor olive oil on on a plate of I think it was prostate cancer cells that I was working with at the time. And I went home and I came back in the morning. All the cells were dead. 

Claudia von Boeselager: Wow. 

Dr. Limor Goren: So I was thinking to myself, geez. All right. Is it every olive oil?

Dr. Limor Goren: Like I go to the supermarket, I pick up a bottle of, you know, the most common $10 olive. Would that be the same? Went down to the supermarket. I picked up a bottle of a $10 olive oil. I poured it on the plate of the same prostate cancer sales. I went home. I came back in the morning and there were double as many cells in the plate.

Claudia von Boeselager: Oh, wow. Why do you think that was? 

Dr. Limor Goren: Because that's what cancer does. Cancer doubles every day ever cancer grows. So basically the olive from the supermarket did nothing to the cancer cells while that fancy olive oil from Greece did something.

Dr. Limor Goren: So I, I knew there was something in it.

Dr. Limor Goren: And then I started sourcing many, many different olives from all over the world from many olive oil producing countries and started comparing their ability to kill cancer cells in a dish.

Dr. Limor Goren: And what I found was that some olives are better and some olives are worse, but the common denominator and what showed really beautiful linear correlation was the higher, the oleocanthal concentration in the olive oil, the better it was of killing cancer cells. So that was very encouraging. 

Claudia von Boeselager: And so, yeah. So what, what happened from there? So you have and I, I, you literally just poured olive oil on the, the cancer cells. You didn't do any extraction process or anything. It was just.

Dr. Limor Goren: I didn't extract it.

Dr. Limor Goren: I made Sort of vinaigrette, I guess, because if you know, like images of how sales are grown in the lab, they're growing Petri dishes with it's like reddish liquid it's, it's basically a buffer a salt buffer. So I verily shipped that together with the olive oil in a century future. And, and kind of made a vinaigrette so it would be, it would absorb better, better.

Dr. Limor Goren: But yeah, I didn't extract it. Other other labs would extract phenols from the olive oil and test purified, but I was really wondering whether just like olive oil as we consume it, have any effect...

Dr. Limor Goren: ...whether that would be the explanation for this phenomena, that we know that people who consume more olive oil are healthier.

Claudia von Boeselager: Yes, exactly. And so what happened from there? You made this discovery and, and what was your next steps? 

Dr. Limor Goren: Well um, publish it, you know, it was published in the scientific literature and then I finished my PhD. I graduated. That was my thesis project. And I just knew that I need to do something with it.

Dr. Limor Goren: I, I didn't feel ready just to move on to a different research project and, and take a research job. And and I knew I wanted to bring this to the masses or educate consumers and advocate for that. I felt my life would be better served outside of the lab, but with the knowledge that I acquired. 

Claudia von Boeselager: Let's talk a little bit more about your book, The Science and Technology of Growing Young. First of all, congratulations on writing a book. Not everyone gets that far, so really fantastic. And I also love the title. I think it sums it up really nicely. What was the purpose behind writing the book?

Claudia von Boeselager: What was your vision when you sat down to start writing it? 

Sergey Young: Yeah, so, well, a number of things, one in longevity, vision fund, we're looking at 200 companies a year and we allow to lapse to the minds, the thoughts of entrepreneurs and greatest scientists. And I thought, I just need to share it with the public.

Sergey Young: It's such a unique access that we joined through our fund. And again, there are very few funds investing in longevity technologies today. So it's a very rare knowledge and I wanted to share it with the audience. So that's number one. Number two, longevity became such a confusing information space. I think it's always been like, but recently it's been a problem.

Sergey Young: Like today you read, you need to do your stem cells injection, like immediately, and then tomorrow you read, well, it's FDA, hasn't approved it. So you just need to wait. It's very risky. And then this happens with everything like putting butter and your coffee. Coffee is right or wrong. Blueberries are great.

Sergey Young: And then next week blueberries eroding it.

Claudia von Boeselager: It toxic.

Sergey Young: Yeah. It's toxic. And the acid from the blueberries erodes your stomach from inside. So a lot of people just going into the default mode, like if this is important enough, this will find me through the medical system. Otherwise I'm not gonna bother because it's really confusing.

Sergey Young: So I thought I just need to bring a more balanced view because we have a lot of brilliant scientists in our scientific advisory board, or the companies that we investing in, we have like access to the best technologies and I'm doing a lot of experiments. I'm not a bio hacker actually am pretty conservative guy, but whenever I have access to something really modern, you know, I'm just doing that... 

Claudia von Boeselager: jumping on it.

Sergey Young: And...

Claudia von Boeselager: You're one level down from the biohacker we have to coin a term Sergey.

Sergey Young: yeah.... That's true, by the way. And I kind of thought, well, this is what I need to share with the public, and I also do believe that we are so focused today on like a negative side of the healthcare system today. So we actually forgot, and we don't really take time to celebrate, think about gene editing and gene therapy.

Sergey Young: 30 years ago, it took 13 years and 3 billion dollars in US to sequence human genome. In fact, they actually wanted to stop the experiment after first two years because they managed to sequence like 1% of the human genome, so they quickly calculated that it's gonna be what a hundred plus to do that, and funny enough and likely the computing power has been more and more affordable and the cost of it has been democratizing itself and they finally completed, well, these days you can sequence human genome, like the most important parts in the course of few hours, and it costs $200.

Sergey Young: Or 30 years ago, the gene editing in the form of, almost like the only technology which was available this days, which is CRISPR, like, genetic scissors. It's been available only to the people who had like nothing to lose on this planet. They were terminally ill, they were about to die and they become like the Guinea pig.

Sergey Young: The only people. Yeah. The Guinea pigs.

Claudia von Boeselager: Yeah, exactly. Like a last resort experiment. 

Sergey Young: Well, right now we are participating in a gene therapy experiment on a global scale. I do believe it's a positive experiments, but like Moderna AstraZeneca. Well, this of all the outcome of gene therapy. Yeah, so that's amazing.

Sergey Young: And this is what happened in the last 30 years, and it's gonna be more and more like our wearables I'm like four full of wearables experiment. Beautiful!

Claudia von Boeselager: I've got the checks. 

Sergey Young: Yep. Yeah. Oura Ring here or continuous glucose monitoring.

Claudia von Boeselager: Okay. 

Claudia von Boeselager: Yeah. I've got those as well.

Sergey Young: So like, If we had taken care of our cars with computers, with sensors, our body and our mind, you know, are much more important.

Sergey Young: We should do that. So then watch the wearable space. All these apple watch feed beats, whoops will become our personalized healthcare devices. I think with addition of like measuring glucose in the blood and measuring our blood pressure in the next couple of years... 

Claudia von Boeselager: mm-hmm

Sergey Young: I think Samsung watch already launched this feature and it's gonna be 90 to 95% of the indicators that we would like to measure on a regular basis.